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Elisabetta Bini
Assistant Professor
 Biochemistry and Micrbiology
Lipman
76 Lipman Drive
New Brunswick, NJ 08901
Phone: 732-932-8165 x101
Fax: 732-932-6535
Email: ebini@rci.rutgers.edu

Expertise Summary
  Regulation of gene expression in response to heavy metals exposure by the hyperthermophilic archaeon Sulfolobus solfataricus is a major area of interest. Microarray technology as well as biochemical and molecular biology tools are employed to monitor gene expression, predict functional roles of unknown genes and characterize proteins and regulatory networks involved in heavy metals metabolism. By providing insights into the physiological response to environmental stress and by elucidating the molecular mechanisms behind it, investigations in this area will contribute to the development of biological solutions to heavy metal remediation problems.

Research Projects
  • Dissecting the Molecular Mechanisms of Metal Metabolism in the Hyperthermophilic Archaeon Sulfolobus

    • Selected Publications
    Archaeal catabolite repression: a gene regulatory paradigm. In: "Archaea: ancient microbes, extreme environments and the origin of life"
      Journal: Adv. Applied Microbiology
     Authors: Bini, E. and P. Blum
    Volume: 50    Pages: 339-366
    Date Published: 2001
    Mapping domain structures in silks from insects and spiders related to protein assembly
      Journal: J. Mol. Biol.
     Authors: Bini E., Knight D. P. and Kaplan D. L.
    Volume: 335    Pages: 27-40
    Date Published: 2004
    Stability of mRNA in the hyperthermophilic archaeon Sulfolobus solfataricus
      Journal: RNA
     Authors: Bini E., V. Dikshit, K. L. Dirksen, M. Drozda and P. Blum
    Volume: 8    Pages: 1129-1136
    Date Published: 2002

     

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